ADHD & Perimenopause: What You Need to Know
Understanding the Connection
If you have ADHD and are entering perimenopause (typically starting in your 40s), you may notice your ADHD symptoms getting worse. This is not your imagination—research shows that nearly all women with ADHD (97.5%) report worsening symptoms during menopause.[1]
Why does this happen? Estrogen, a hormone that declines during perimenopause, plays an important role in brain function, particularly in areas that affect attention, memory, and impulse control. When estrogen levels drop and fluctuate during perimenopause, it can make existing ADHD symptoms worse.[2-3]
What Symptoms Might Worsen
Women with ADHD going through perimenopause often experience:
Increased difficulty concentrating and focusing
More forgetfulness and "brain fog"
Worsening executive function (planning, organizing, completing tasks)
Greater emotional sensitivity and mood swings
More severe sleep problems
Reduced effectiveness of ADHD medications that previously worked well[2][4]
Women with ADHD also tend to have more severe perimenopausal symptoms overall compared to women without ADHD, including hot flashes, mood changes, and sleep disturbances.[5]
What You Can Do
Track Your Symptoms
Keep a simple daily log of your ADHD symptoms, mood, sleep quality, and any perimenopausal symptoms (hot flashes, night sweats, etc.). This helps you and your healthcare provider identify patterns and adjust treatment as needed.[2]
Talk to Your Healthcare Provider
Discuss both your ADHD and perimenopausal symptoms with your healthcare provider. Many women find that their ADHD is overlooked when they seek help for perimenopausal symptoms, or vice versa. Make sure your provider understands you're dealing with both.[2]
Consider Treatment Adjustments
Your ADHD medication may need adjustment during perimenopause. Some women report that their usual dose becomes less effective during this time. Work with your healthcare provider to find the right approach for you.[2][4]
Explore Hormone Therapy
While research specifically on hormone replacement therapy (HRT) for ADHD symptoms is limited, HRT can help with perimenopausal symptoms like hot flashes and mood changes. Discuss with your healthcare provider whether HRT might be appropriate for you, considering your individual health history and symptoms.[2][5]
Prioritize Self-Care
Regular exercise can help with both ADHD symptoms and perimenopausal symptoms
Good sleep hygiene is especially important as both conditions can disrupt sleep
Stress management techniques like mindfulness or yoga may help
Healthy nutrition supports overall brain and hormonal health[6]
Seek Support
Consider joining a support group for women with ADHD or women going through perimenopause. Connecting with others who understand your experience can be invaluable. Some specialized treatment programs focus specifically on women with ADHD and hormonal changes.[7]
Important to Remember
Your worsening symptoms are real and have a biological basis
You're not alone—this is a common experience for women with ADHD
Treatment options are available, even though research in this area is still developing
With proper support and management, you can navigate this transition successfully
Questions to Ask Your Healthcare Provider
How might perimenopause be affecting my ADHD symptoms?
Should we adjust my ADHD medication?
Would hormone replacement therapy be appropriate for me?
What other treatments might help with my symptoms?
Should I see a specialist who understands both ADHD and menopause?
References
ADHD in Females: Survey Findings on Symptoms Across Hormonal Life Stages.
Osianlis E, Thomas EHX, Li Q, et al. Journal of Psychiatric Research. 2025;193:208-215. doi:10.1016/j.jpsychires.2025.11.035.
Attention-Deficit/Hyperactivity Disorder and the Menstrual Cycle: Theory and Evidence.
Eng AG, Nirjar U, Elkins AR, et al. Hormones and Behavior. 2024;158:105466. doi:10.1016/j.yhbeh.2023.105466.
Wynchank D, de Jong M, Kooij SJJS. European Psychiatry : The Journal of the Association of European Psychiatrists. 2025;69(1):e1. doi:10.1192/j.eurpsy.2025.10120.
Wynchank D, Sutrisno RMGTMF, van Andel E, Kooij JJS. Journal of Clinical Medicine. 2025;15(1):121. doi:10.3390/jcm15010121.
Perimenopausal Symptoms in Women With and Without ADHD: A Population-Based Cohort Study.
Jakobsdóttir Smári U, Valdimarsdottir UA, Wynchank D, et al. European Psychiatry : The Journal of the Association of European Psychiatrists. 2025;68(1):e133. doi:10.1192/j.eurpsy.2025.10101.
Integrative Approaches to Perimenopause.
Kennard A, Saunders KT. The American Journal of Medicine. 2026;:S0002-9343(26)00013-6. doi:10.1016/j.amjmed.2025.12.024.
de Jong M, Wynchank DSMR, Michielsen M, Beekman ATF, Kooij JJS. Journal of Clinical Medicine. 2024;13(7):2106. doi:10.3390/jcm13072106.